FastGene MagnaStands

Magnetic Beads have been used for a long time to isolate nucleic acids as well as recombinant proteins. The purification was however problematic, often with carry over when the pellet was disturbed or with contamination when the supernatant was not completely removed.

The FastGene^® MagnaStands solve both issues. By creating a pellet at the side walls rather than at the bottom, the MagnaStands allow with their very strong neodymium magnets the complete removal of the supernatant without touching the pellet.

Additionally, with the MagnaStand 1.5, the vertical position is adjustable allowing the magnets' place to be fine tuned on the tube according to volume used in the purification.

Neodymium Magnets for faster attraction of magnetic particles

The Neodymium magnets are the strongest permanent magnets in the world. The advantages of using such strong magnets are:

• Very quick separation of magnetic beads from the solution
• Stable pellet even when resuspending
• Complete collection of the magnetic beads for less material loss

Together with the vertical position of the magnets, the magnetic strength gives you the optimal solution for purification of magnetic beads.

"More and more applications are performed using magnetic beads, so that a magnetic stand is required which can handle very small volumes. Especially in the genomics research field, where massively parallel sequencing is performed, it is essential for an ideal magnetic stand that is used for the purification of DNA and RNA, to be compatible with a variety of commercially available PCR tubes and plates.

The available magnetic stands could not capture the magnetic beads firmly or provide an easy handling for the researcher. The handling of the FastGene^® MagnaStands is easy, without any loss of magnetic beads during purification even when very few µl of liquid volume were used. Hence, it is the solution for the well-known and common problem of sample loss due to magnetic beads being aspirated by the pipette during a purification using a small sample volume.

The FastGene^® MagnaStand 0.2 and the FastGene^® MagnaStand 1.5 can be used for the purification of small number of samples.

The FastGene^® MagnaStand 96 is useful for the purification of a large number of samples, e.g. for single-cell genomic research.

All FastGene^® MagnaStands are the best tool to easily purify magnetic beads from small volumes, since the magnetic beads are firmly held in one position of the tube wall."

Dr. Yohei Sasagawa*

Bioinformatics Research Unit, Advanced Center for Computing and Communication, RIKEN, Japan

*Dr. Yohei Sasagawa is a researcher who collaborated with Nippon Genetics to develop the FastGene^® MagnaStands for his NGS library preparations.

*Translated to English by Nippon Genetics

"Actually Postdoc using it is truly happy with it, she will recommend to anybody will ask".

Lab Manager, University Basel

"The magnetic stand FastGene® Magna Stand (FG-SSMAG2) from Nippon Genetics was implemented in the diagnostic lab of our institute to isolate genomic DNA from patients, for a SureSelectQXT Target Enrichment (Agilent), before being sequenced using a MiSeq instrument (Illumina). The FastGene® Magna Stand has been used in all steps where AMPure XP beads (BeckmanCoulter) or Dynabeads (Life Technology) were utilized.
The handling of the FastGene® Magna Stands is very easy and the results obtained so far are good. The pellet stays, as desired, at the side of the tube wall, enabling an easy removal of the supernatant. In some cases, the complete removal of the elution was possible. The FastGene® Magna Stand is compact and robust. We are very satisfied with it and would recommend it any time!"

Simone Rost, PhD - Institute of Human Genetics - University of Würzburg - Germany

• Separation of magnetic beads.
• NGS library preparation
• recombinant protein

MagnaStand 1.5

 For large volumes using 1.5 ml tubes. The position of the magnets is adjustable in horizontal as well as vertical axis.

• Perform up to 8 purifications in parallel
• Extra large magnets for larger volumes
• Adjust the magnet position to the volume of your sample

MagnaStand 0.2

For purifications of ultra low volumes (down to 5 µl) using normal PCR-tubes. The optimal horizontal position can be fine-tuned.

The FastGene® MagnaStand (FG-SSMAG2) from Nippon Genetics was implemented in the diagnostic lab of our institute to isolate genomic DNA from patients, for a SureSelectQXT Target Enrichment (Agilent), before being sequenced using a MiSeq instrument (Illumina).  The FastGene® Magna Stand has been used in all steps where AMPure XP beads (BeckmanCoulter) or Dynabeads (Life Technology) were utilized.
The handling of the FastGene^® Magna Stands is very easy and the results obtained so far are good. The pellet stays, as desired, at the side of the tube wall, enabling an easy removal of the supernatant. In some cases, the complete removal of the elution was possible. The FastGene^® Magna Stand is compact and robust. We are very satisfied with it and would recommend it any time!
Simone Rost, PhD - Institute of Human Genetics - University of Würzburg - Germany

• Perform up to 8 purifications in parallel
• Optimized for extra small volumes
• Adjust the magnet position for closer contact to the tube

MagnaStand 96

• Perform up to 96 purifications in parallel
• Compatible with Full-, Semi-, and Non-skirted (with adapter) 96 well plates